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Here is a small list of the testing available through our partnership with Evexia Diagnostics®
Neuro-Adrenal Panel
This test gives a complete picture of how your adrenal gland is working. It measures cortisol levels throughout the day, DHEA, and six key neurotransmitters (which can either calm you down or excite you). You should consider this test if you have the symptoms like these:
● Mood disorders● Depression● Anxiety ● Addiction● Dependency● Chronic illness● Immune Deficiency● Low Libido● Sexual Dysfunction
Urinary neurotransmitter levels give a snapshot of the body's overall ability to produce and break down neurotransmitters, which are chemicals that transmit signals in the nervous system. These levels reflect the entire body's neurotransmitter activity, not just the brain's, because it's hard to measure neurotransmitters directly in the brain. About 20% of the neurotransmitters found in urine come from the brain. Since the same processes for neurotransmitter metabolism occur both in the brain and the rest of the body, changes in urinary neurotransmitter levels can give valuable clinical insights and may be linked to various symptoms like cognitive issues, mood changes, fatigue, sleep problems, cravings, addictions, and pain.
Here's a simplified breakdown of specific neurotransmitter issues and their effects:
High Serotonin:
Can cause anxiety, agitation, and digestive issues. It can increase due to low-protein or high-carbohydrate diets, insulin, tryptophan or 5-HTP supplements, and some medications. L-theanine might help with serotonin function.
Low Norepinephrine:
Linked to depression, mood swings, fatigue, trouble concentrating, and lack of motivation. It needs vitamin C, copper, B3, and the amino acid L-tyrosine for production. Supplements like L-theanine and Mucuna pruriens might help.
High Epinephrine:
Associated with stress, anxiety, agitation, insomnia, and high blood pressure. Exercise before urine collection can raise its levels. Its metabolism requires vitamins B2, B3, SAMe, magnesium, and iron. L-theanine might help regulate its effects.
Low Glutamate:
Connected to depression, addictive behaviours, mental fatigue, and decreased mental stimulation. L-glutamine can help as it’s a precursor.
Low GABA:
Can cause anxiety, poor impulse control, major depression, pain, and decreased activity. Vitamin B6 is necessary for its production, and L-theanine, GABA supplements, and glutamine might help.
High Histamine:
May cause allergy-like symptoms, gastrointestinal issues, skin inflammation, wakefulness, and insomnia. It can be elevated by histamine-rich foods, certain medications, bacterial production, and zinc deficiency. Breaking down histamine requires SAMe and copper.
Basic Salivary Hormone Panel
The Basic Hormone Profile provides a basic evaluation of the sex hormones and a brief glimpse at adrenal function with the AM cortisol level. This profile is useful when retesting patients who have begun hormone therapy, but we encourage use of the Comprehensive Profile for initial evaluation.
This is the minimal test recommended for symptoms that include:
Men Experiencing
● Decreased libido● Erectile dysfunction● Loss of stamina● Decrease ni mental sharpness● Reduced muscle size● Tearful episodes● Increased moodiness● Metabolic syndrome● Prostate enlargement or cancer● Hot flashes● Irritability
Women Experiencing
● Hot flashes● Anxiety/Depression● Night sweats● Breast tenderness● Irritability● Forgetfulness● Irregular menstrual cycles ● Vaginal dryness● Urinary incontinence● Uterine fibroids● Increased facial / body hair ● Acne
Comprehensive Salivary Hormone Panel
The Comprehensive Hormone Panel is the starting point for initial assessment of hormonal status and endocrine function and includes estradiol (E2), progesterone, testosterone, DHEA and four cortisols. This panel is useful with male and female patients because it looks at the full diurnal cortisol pattern; it is especially important in patients who are experiencing the following symptoms in addition to the symptoms listed for the Basic Hormone Panel:
● Multiple chemical sensitivity● Weight gain● High blood sugar● Elevated lipids● Insomnia● Chronic fatigue● Fibromyalgia
Comprehensive Plus Salivary Hormone Panel
The Comprehensive Plus Panel builds on the Comprehensive Hormone Panel by adding estrone (E1), estriol (E3), and the Estrogen Quotient (EQ). The EQ is a simple ratio that compares the cancer-protective estrogen (E3) to the more active estrogens (E1 and E2). This ratio helps assess breast cancer risk:
● An EQ less than 1.0 indicates a higher risk of breast cancer.● An EQ greater than 1.0 indicates a lower risk.● For optimal protection, an EQ above 1.5 is ideal.
Since the research on EQ and estriol's protective properties is specific to women, this panel is recommended for women only. Consider this panel for patients with the following conditions:
● Increased risk of developing breast cancer● History of breast cancer or other hormonally sensitive cancers● Personal or family history of autoimmune disease● PCOS
DNA Methylation; buccal Swab
The DNA Methylation Pathway Profile helps identify genetic changes (single nucleotide polymorphisms, or SNPs) that can impact health and disease risk. By identifying these SNPs, doctors can better support patients in optimizing their health and wellness. This test screens for genetic variations that affect important processes such as:
● Methionine metabolism● Detoxification● Hormone balance● Vitamin D function
SNPs are common DNA variations that can influence how well these processes work. Unlike rare disease mutations (like the gene for Huntington's disease, which causes the disease if inherited), SNPs don't directly cause diseases but can increase the risk for certain conditions. These SNPs can affect proteins, enzymes, or cell receptors in subtle but significant ways. Often, multiple SNPs need to be present to impact the body's metabolic or biochemical functions.
Environmental factors like diet, lifestyle, nutrition, and exposure to toxins can modify the effects of SNPs. For instance, detoxification and methylation processes become crucial if a person has been exposed to toxins such as mercury, lead, or BPA. These toxins can inhibit enzymes necessary for detoxification and other biochemical processes.
The DNA Methylation Pathway Profile is particularly useful for identifying SNPs related to:
● Insulin sensitivity● Bone health● Cancer risks● Cardiovascular health● Detoxification processes● Fertility● Mitochondrial function and metabolism● Neurotransmitter balance
This test helps clinicians tailor lifestyle changes and nutritional support to improve health and reduce disease risks based on an individual's genetic makeup. Additionally, the Plasma Methylation Profile can provide further insights by assessing key metabolites, helping to understand how genetic and environmental factors are affecting the patient's health.